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NEXIUM Pediatric GERD Information
- Among patients studied in the 10-mg and 20-mg dose groups who had EE at baseline and follow-up endoscopies (n=34), 85.3% of patients had resolution of EE1
- Although most of the patients who had a follow-up endoscopy at the end of 8 weeks were healed, spontaneous healing cannot be ruled out
The primary objective was to evaluate the safety profile of NEXIUM in patients 1 to 11 years of age1
— No clinically important safety findings and trends in hematology, clinical chemistry, urinalysis, vital signs, or physical examination were observed (n=108)*2
* One patient was not evaluable for safety because the patient did not have any post-baseline safety data.
NEXIUM healed most patients 1 to 11 years of age with erosive esophagitis (EE)

Data from a phase III, multicenter, randomized, open-label to treatment, double-blinded to dose, parallel-group study evaluating the safety and clinical outcome of NEXIUM in patients aged 1 to 11 years with GERD, treated once daily with NEXIUM 5 mg, NEXIUM 10 mg, or NEXIUM 20 mg for 8 weeks. Dosing was determined by patient weight. A total of 109 patients of both sexes with endoscopically proven GERD were enrolled, with 101 patients completing the study. Of the 109 patients, 53 had EE at baseline (51 had mild, 1 moderate, and 1 severe).1
Patients were considered healed if their final follow-up endoscopy showed no signs of erosions.
† Among all patients studied who had a follow-up endoscopy (n=45), overall resolution of EE was 88.9% (n=40) across varying grades of EE.
Patient Support
Help eligible patients save on NEXIUM prescriptions with the Purple Plus™ Savings Card.
Educational Resources
Download and print helpful GERD-related resources for your patients.





(PDF – 303 KB) for NEXIUM.