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NEXIUM Works for Me

Proven Healing of Erosive Esophagitis vs Other PPIs

In 5 different studies, NEXIUM® (esomeprazole magnesium) demonstrated excellent erosive esophagitis (EE) healing rates vs omeprazole*, lansoprazole, or pantroprazole (n>13,500, of whom >7000 received NEXIUM).1-5

*In 2 other studies, NEXIUM vs omeprazole, P=NS.6-7

NEXIUM Healing comparison: esomeprazole magnesium vs omeprazole, lansoprazole or pantroprazole   

Educational Resources

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There's just something about Purple

Since its approval in 2001, NEXIUM has been prescribed more than 147 million times.11

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Approved Uses

Healing of Erosive Esophagitis (EE)

NEXIUM 40 mg and NEXIUM 20 mg are indicated for short-term treatment (4 to 8 weeks) in healing and symptomatic resolution of diagnostically confirmed EE.

Maintenance of Healing of EE

NEXIUM 20 mg is indicated to maintain symptom resolution and healing of EE. Controlled studies did not extend beyond 6 months.

Symptomatic GERD

NEXIUM 20 mg is indicated for the treatment of heartburn and other symptoms associated with GERD.

Pediatric Use

NEXIUM is indicated for the short-term treatment (up to 8 weeks) of GERD (symptomatic GERD and healing of EE) in patients 1 to 17 years of age. Pediatric use is supported by extrapolation of results from studies that supported the approval for NEXIUM for adults and safety and pharmacokinetic studies performed in pediatric and adolescent patients.

Effectiveness has not been demonstrated in patients less than 1 year of age. Safety and effectiveness for other pediatric uses have not been established.

Important Safety Information

Please click here for the full Prescribing Information pdf (PDF – 303 KB) for NEXIUM.

Please see the full Prescribing Information available at the Web site for NEXIUM.

References
  1. Labenz J, Armstrong D, Lauritsen K, et al. Aliment Pharmacol Ther. 2005;21:739-746.
  2. Kahrilas PJ, Falk GW, Johnson DA, et al. Aliment Pharmacol Ther. 2000;14:1249-1258.
  3. Fennerty MB, Johanson JF, Hwang C, et al. Aliment Pharmacol Ther. 2005;21:455-463.
  4. Castell DO, Kahrilas PJ, Richter JE, et al. Am J Gastroenterol. 2002;97:575-583.
  5. Richter JE, Kahrilas PJ, Johanson J, et al. Am J Gastroenterol. 2001;96:656-665.
  6. Schmitt C, Lightdale CJ, Hwang C, et al. Dig Dis Sci. 2006;51:844-850.
  7. Lightdale CJ, Schmitt C, Hwang C, et al. Dig Dis Sci. 2006;51:852-857.
  8. Prescribing Information for NEXIUM.
  9. Data on file, eSTaR #268266.
  10. Data on file, eSTaR #267442.
  11. Data on file, eSTaR #263225.