Symptom Relief in Patients with Erosive Esophagitis (EE) Over 24 Hours1-3
In patients with EE, NEXIUM provided day and night symptom relief over 24 hours1-3
85%–91% heartburn-free nights
- The percent of heartburn-free* nights with NEXIUM 40 mg at week 4 ranged from 85%–91%, based on patient diaries from 3 studies.†1-3
- With NEXIUM 20 mg, the percent of heartburn-free† nights at week 4 ranged from 84%–86%, based on patient diaries from 2 studies. †2,4
73%–75% heartburn-free days
- The percent of heartburn-free* days with NEXIUM 40 mg at week 4 ranged from 73%–75%, based on patient diaries from 3 studies†1-3
- With NEXIUM 20 mg, the percent of heartburn-free† days at week 4 ranged from 69%–73%, based on patient diaries from 2 studies. †2,4
*Heartburn-free defined as patient-recorded symptom of “none.”
†Secondary endpoints from 4 multicenter, randomized, double-blind trials comparing oral doses of NEXIUM vs omeprazole, administered once daily to patients with endoscopically diagnosed EE. Primary endpoint was healing of EE at week 8 (N=2425),1 (N=1960),2 (N=1148),3 (N=1175).4
NEXIUM 20 mg is the FDA-approved dose for the symptom relief of GERD.
NEXIUM 40 mg and NEXIUM 20 mg are the FDA-approved doses for the healing of EE. There is no correlation between symptom relief and the healing of EE with NEXIUM.
Next: Prevalence of EE
