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Symptom Relief
In patients with Erosive Esophagitis (EE)...
NEXIUM: day and night symptom relief over 24 hours1-3
Daytime Heartburn Relief:
In 5037 erosive esophagitis (EE) patients…
- 90% of patients taking NEXIUM 40 mg QD (n=2521) reported daily heartburn relief at week 4,* and 89% of patients experienced daily heartburn relief with lansoprazole 30 mg QD (n=2516; P=NS)*†1,2
* Secondary endpoint from a multicenter, randomized, double-blind study (n=5037), comparing NEXIUM 40 mg with lansoprazole 30 mg administered once daily to patients with endoscopically diagnosed erosive esophagitis (EE).1,2 Primary endpoint was healing of EE at week 8.
† Heartburn relief defined as investigator-recorded symptom of “none” or “mild.”
Nighttime Heartburn Relief:
In 1860 EE patients…
- 92% of patients taking NEXIUM 40 mg QD (n=909) reported heartburn-free nights at week 4,‡ and 90% of patients experienced heartburn-free nights with lansoprazole 30 mg QD (n=951; P=NS)§1,3
‡ Secondary endpoint from a multicenter, randomized, double-blind study (n=1860), comparing NEXIUM 40 mg with lansoprazole 30 mg administered once daily to patients with endoscopically diagnosed EE.1,3 Primary endpoint was healing of EE at week 8.
§ Heartburn-free nights defined as patient-recorded symptom of “none.”
//Primary endpoint from a multicenter, randomized, double-blind, parallel-group, 8-week trial comparing oral doses of NEXIUM 40mg with lansoprazole 30mg administered once daily to patients with endoscopically diagnosed EE.
- NEXIUM 40 mg and NEXIUM 20 mg are the FDA-approved doses for the healing of EE
NEXIUM Data
Learn more about NEXIUM healing rates versus omeprazole and lansoprazole.





(PDF – 303 KB) for NEXIUM.