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The NEXIUM Savings Card

Help your patients save on their prescriptions for NEXIUM

The NEXIUM Savings Card can reduce out-of-pocket cost for eligible patients*

With The NEXIUM Savings Card, eligible patients can save on their next 12 prescription fills of NEXIUM at the pharmacy.*†‡

  • Eligible patients who also have commercial prescription drug coverage with a co-pay of more than $18 pay the first $18 of their co-pay and The NEXIUM Savings Card covers up to the next $50 for up to 12 fills
  • Eligible patients can go to www.purplepill.com to print out a card. Each card will be pre-activated and ready to use at the pharmacy immediately
  • Eligible patients can receive their NEXIUM Savings Card directly from their physician when NEXIUM is prescribed. Physicians may download and print the card to share with their patients


Offer is void for mail order and is not valid for prescriptions purchased under Medicaid, Medicare, or similar state or federally funded health care programs and is void where prohibited by law, taxed, or restricted. For Massachusetts residents, this offer is not valid.

The NEXIUM Savings Card is pre-activated so your patient can begin saving immediately.

NEXIUM Savings Card examples

*Insured patients with a co-pay of $18 or less are not eligible for this offer.
The card expires after 12 fills or 14 months after first use, whichever comes first.

Eligibility: This offer is good for qualified customers for the purchase of at least a 30-day supply of NEXIUM and may not be used for any other product. This offer is good for the purchase of NEXIUM manufactured for AstraZeneca LP and lawfully purchased from an authorized retailer in the United States or its territories. This offer may not be combined with any other offer, including any coupon, discount, or prescription savings card program. It is void for mail order and is not valid for prescriptions purchased under Medicaid, Medicare, or similar state or federally funded health care programs and is void where prohibited by law, taxed, or restricted. For Massachusetts residents, this offer is not valid. Card must be presented along with a valid prescription for NEXIUM at the time of purchase. Patients who have prescription coverage with a co-pay exceeding $18 may receive up to $50 in savings on each fill for NEXIUM (up to 12 fills). Patients who do not have prescription coverage, that is, patients who pay cash for their prescriptions, may receive $50 in savings on each fill for NEXIUM (up to 12 fills). Offer is limited to one savings card per person for up to 12 fills of NEXIUM within 14 months of first use. Offer good only in the United States and its territories. AstraZeneca reserves the right to discontinue this offer at any time.

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Help eligible patients save on NEXIUM prescriptions with The NEXIUM Savings Card.

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Important Safety Information

  • NEXIUM is contraindicated in patients with known hypersensitivity to any component of the formulation or to substituted benzimidazoles
  • Symptomatic response to therapy does not rule out the presence of gastric malignancy
  • Atrophic gastritis has occasionally been noted with long-term therapy with omeprazole
  • Long-term and multiple daily dose proton pump inhibitor (PPI) therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist, or spine
  • Hypomagnesemia has been reported rarely with prolonged treatment with PPI therapy and may require discontinuing PPI therapy
  • Concomitant use of NEXIUM and St. John's wort or rifampin can substantially decrease NEXIUM concentrations. Avoid concomitant use
  • Concomitant use of NEXIUM and atazanavir or nelfinavir is not recommended. NEXIUM may increase the plasma levels of saquinavir. Dose reduction of saquinavir should be considered
  • Patients treated with PPIs and warfarin concomitantly may need to be monitored for increases in INR and prothrombin time. Esomeprazole may interfere with the absorption of drugs for which gastric pH affects bioavailability (eg, ketoconazole, iron salts, and digoxin)
  • NEXIUM may increase systemic exposure of cilostazol and one of its active metabolites. Consider dose reduction
  • NEXIUM I.V. should be used only when oral therapy with NEXIUM is not possible or appropriate
  • In adults, the most frequently reported adverse reactions (ARs) with NEXIUM include headache, diarrhea, and abdominal pain
  • The ARs reported at a frequency of 1% or greater with NEXIUM I.V. in clinical trials were headache, flatulence, nausea, abdominal pain, injection site reaction, diarrhea, dry mouth, dizziness/vertigo, constipation, and pruritus
  • In pediatric patients 1 to 17 years of age, the most frequently reported ARs with NEXIUM include headache, diarrhea, abdominal pain, nausea, and somnolence

Approved Uses

NEXIUM 40 mg and 20 mg are indicated for short-term treatment (4 to 8 weeks) in healing and symptomatic resolution of diagnostically confirmed erosive esophagitis (EE). NEXIUM 20 mg is indicated to maintain symptom resolution and healing of EE (controlled studies did not extend beyond 6 months), and for short-term treatment (4 to 8 weeks) of heartburn and other symptoms associated with GERD.

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